In
its
latest
report,
WHO
provides
a
comprehensive
assessment
of
the
TB
epidemic
and
progress
in
prevention, diagnosis and
treatment
at
global, regional and
country
levels.
The
2025
edition
draws
primarily
on
data submitted annually
by
national ministries
of
health.
In
2025,
184
countries
and
areas,
representing more
than
99%
of
the
world’s
population
and
TB
burden,
reported
their
data.
According
to
the
report,
progress remains far
behind
End
TB
Strategy
targets
as
funding
continues
to
stagnate.
“Despite
many
gains,
global
progress
levels remain far
from
meeting
the
End
TB
Strategy
targets.
A
major
obstacle
is
global
funding
for
TB,
which
has
stagnated
since
2020.
In
2024,
only
US$5.9
billion was
available
for
prevention,
diagnosis,
and
treatment,
just
over
a
quarter
of
the
US$22
billion annual
target
set
for
2027,”
the
summary
noted.
It
further
warned
that
looming
cuts
to
international
donor
funding
from
2025
pose
a
significant
threat.
Modelling
shows
that
sustained
reductions
could
lead
to
up
to 2
million additional deaths and 10
million
more
TB
infections between
2025
and
2035.
Global
TB
research
funding
is
also
lagging,
reaching
only
US$1.2
billion in
2023,
24%
of
the
target.
However,
scientific
activity
continues
to grow: as
of
August
2025,
63
diagnostic
tests
were
in
development
and
29
drugs
were
undergoing
clinical
trials,
compared
to
just
eight
in
2015.
In
addition,
18
vaccine
candidates
are
in
clinical
trials,
including
six
in
Phase
3.
WHO
continues
to
steer
global
vaccine
development
efforts
through
the
TB
Vaccine
Accelerator
Council.
Dr Tereza Kasaeva,
Director
of
the
WHO
Department
for
HIV,
TB,
Hepatitis
and
STIs,
urged
countries
to
reinforce
political
commitment
and
increase
domestic
investment
to
avoid
reversing
gains
made
in
recent
years.
“We
are
at
a
defining
moment
in
the
fight
against
TB,”
she
said.
“Funding
cuts
and
persistent
drivers
of
the
epidemic
threaten
to
undo
hard-won
gains,
but
with
political
commitment,
sustained
investment,
and
global
solidarity,
we
can
turn
the
tide
and
end
this
ancient
killer
once
and
for
all.”